The Ingredients in BIOSKINBALM

The full list of ingredients in BIOSKINBALM is: (1) Water; (2) Rose Hip Seed Oil; (3) Helix Aspersa Müller Glycoconjugates, the strongest biological ingredient known for healthy skin, produced by a living being to function as a biological antibiotic, an inflammatory-regulator, an antioxidant, a moisturizer & a stimulator of scarless healing & skin regeneration; (4) Olive Oil emulsifier, surfactant, and squalene by-products that refill the lipid content of the skin obstructing the assimilation of allergens and toxins and acting as antioxidants; (5) Seaweed Extract, a rich supply of oligoelements that are needed for cellular development, (6) Hyaluronic Acid moisturizer a biologically occuring skin substance with the ability of retaining more water than any other known hydrator; (7) Chamomile for inflammatory skin conditions. It is good for sensitive skin, and helpful in dermatitis; (8) Pentavitin™, Saccharide Isomerate, a carbohydrate complex identical to that present in the stratum corneum of the skin that holds water by strongly binding water to keratin; (9) A preservative made only with the following botanical extracts in minute quantities: Origanum Vulgare (Oregano) Leaf Extract (and) Thymus Vulgaris (Thyme) Extract (and) Cinnamomum Zeylanicum (Cinnamon) Bark Extract (and) Rosmarinus Officinalis (Rosemary) Leaf Extract (and) Lavandula Augustifolia (Lavender) Flower Extract (and) Citrus Medica Limonum (Lemon) Peel Extract (and) Mentha Piperita (Peppermint) Leaf Extract (and) Hydrastis Canadensis (Golden Seal) Root Extract (and) Olea Europaea (Olive) Leaf Extract; and nothing else.

Biochemical investigation of the fluid collected from snails of the species Helix Aspersa Müller proves it contains an heterogeneous compound of glycoconjugates, were we can find glycosaminoglycans, proteoglycans, glycoproteins, copper peptides, co-enzymes and zinc participating in the production of superoxide dismutase antioxidant with rich biological functions that play essential roles for the sustaining of healthy tissues.

Glycosaminoglycans (GAGs) are relatively large molecules composed of polysaccharide side chains attached to a core backbone of protein, forming a proteoglycan. Each polysaccharide side chain consists of a disaccharide repeat unit composed of hexosamine linked to uronic acids (either iduronic or glucuronic acid). The hexosamine is a glucosamine in heparin, and heparin sulfate and a galactosamine in dermatan sulfate (DS). The disaccharide units are heavily modified and the number of modifications allows for a large structural and functional diversity; it is the composition of the disaccharide side chains that defines the individual GAGs.

The disaccharides are often heavily sulfated and hence strongly negatively charged, and this may explain the pronounced ability of the GAGs to interact with proteins such as growth factors, enzymes, and chemokines. In the body, GAGs are present in mast cells (as heparin), in the extracellular matrix (ECM) and attached to cell surfaces. Clinically, GAGs are widely used for their anti-coagulating effects. Physiologically, the role of the GAGs has still to be fully determined. However, they are known to interact strongly with several growth factors, and therefore, GAGs are assumed to influence growth of normal as well as neoplastic (abnormal and cancer) cells and in the regulation of angiogenesis (growth of blood vessels) .

Order Out of Caos: The Function of Glycoconjugates

Proteoglycans, Glycoproteins and Glycosaminoglycans (GAGs) are active regulators of the cell's activities. They collaborate in cell-matrix relations and take an important biological role in fibroblasts proliferation and in the differentiation and migration of all cells by effectively modulating the cell’s phenotype.

Fibroblasts are the cells in the basement membrane of the skin that give rise to all components of the extracellular matrix, in particular to collagen, elastin, glycosaminoglycans and proteoglycans in the skin matrix.

The basement membrane (BM) is a specialized form of extracellular matrix (ECM) and has recently been recognized as an important regulator of cell behaviour, rather than just a structural feature of tissues. The BM mediates tissue compartmentalization and sends signals to epithelial cells about the external microenvironment.

Proteoglycans are intrincated macromolecules formed by a core protein and one or more covalently attached glycosaminoglycan chain. The biological activities of proteoglycans appear primarely from the structurally regent glycosaminoglycans emanating from the protein core of the molecule. A big number of animal species have GAGs and mollusks are a especially rich source of these glycomolecules or polysaccharides.

GAGs are often found in the outer matrix of vertebrate and invertebrate tissues. Structural investigation shows that GAGs in invertebrate animal species often include odd variations of sulfate distribution and uronic acids. The most important glycoconjugate of the land snail liquid solution is a glycosaminoglycan, with an atypical structure when put next to other recognized glycosaminoglycans. It is secreted from granules inside the snail's body and is localized on the external surface as a result of exposure of the snail to stress.

What is the importacne of glycosaminoglycans?

Glycosaminoglycans are needed in regular animal growing and in the prevention of a lot of conditions; glycans seem to act as scaffolds that mediate communications among cells and proteins.

Carbohydrates are very important to life. In their simple form, they work as a main energy source that sustains life. For the most part, anyway, carbohydrates do not exist as simple sugars but as intrincated molecular conjugates, or glycans.

Glycans can have several shapes and sizes, from one line chains (polysaccharides) to extremely branched molecules bristling with antennae-like arms. And despite proteins and nucleic acids such as DNA have traditionally brought far more scientific attention, glycans are also key to life. They are ubiquitous in nature, forming the intrincate sugar cover that circles the cells of basically every organism and occupying the places among these cells. As part of this so-called extracellular matrix, glycans, with their various chemical structures, play an important part in communicating very important biochemical signals into and among cells. In this way, these sugars guide the cellular transmmition that is very important for normal cell and tissue development and physiological function.

GAGs come to be a very important component of connective tissues. GAG chains may be covalently attached to a protein to form proteoglycans.

Dermatan sulfate is a glycosaminoglycan that can be found specially in skin, but also in blood vessels, heart valves, tendons, and lungs. Dermatan sulfate may have a part in coagulation, cardiovascular disease, carcinogenesis, infection, wound recovery, and fibrosis.

Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) made of one chain of alternating sugars (N-acetyl-galactosamine and glucuronic acid). It is normally found attached to proteins as part of a proteoglycan. A chondroitin chain can contain over 100 individual sugars, each of which can be sulfated in variable ways and quantities. Understanding the functions of such diversity in chondroitin sulfate and related glycosaminoglycans is an important goal of glycobiology. Chondroitin sulfate is a major structural component of cartilage and gives much of its tolerance to compression.

Complex sugars, or glycans, that are often knitted to proteins, cover the exterior of cells and fill the spaces among them. Very important in regular animal development and in the prevention of a lot of diseases, glycans appear to act as scaffolds that mediate communications among cells and proteins.

The Interesting Science of Glycobiology.

Heterogeneus carbohydrates, molecules that are mostly relevant for communication between cells, are coming under systematic study and shed light on the effects of the components of the snail secretions when used for skin care.

The central model of actual molecular biology is that biological information goes from DNA to RNA to protein. The strenght of this approach resides not only in its template-driven precision, but also in the capacity to manage any one class of molecules supported on recognition of another one, and in the diagrams of sequence homology and relatedness that predict activity and reveal evolutionary connections. With the expectedforthcoming finalization of the genomic catenations of humans and a list of other usually analized model beings, even more spectacular gains in the comprehension of biological elements are anticipated. However, there’s commonly an inclination to assume the following extension of the main model: DNA to RNA to PROTEIN to CELL to ORGANISM.

In actual fact, elaborating a cell implies having two other major classes of molecules: lipids and carbohydrates. These molecules can act as intermediates in creating energy, as marking molecules, or as structural elements. The structural main roles of carbohydrates get incredibly considerable in constructing heterogeneous multicellular organs and organisms, which requires interactions of cells with one another and with the surrounding matrix. Indeed, all cells and a great deal of macromolecules in nature have a dense and heterogeneous display of covalently united sugar chains (called oligosaccharides or glycans).

In some cases, these glycans can also be free-standing entities. Because most glycans are on the outer surface of cellular and secreted macromolecules, they are in a place to modulate or intercede a wide variety of events in cell-cell and cell-matrix interactions vital to the development and function of a complex multicellular organism. They’re also in a location to mediate interactions among organisms (e.g., among host and parasite).

Plus, simple, extremely dynamic protein-bound glycans are very abundant in the nucleus and cytoplasm, where they appear to work as managing switches.

During the first part of this century, the chemistry, biochemistry, and biology of carbohydrates were extremely prominent matters of study. Nevertheless, during the initial years of the modern revolution in molecular biology, reseach about glycans looked small next to those of other major classes of molecules. This was largely due to their natural structural complexity, the difficulty in easily concluding their sequence, and the reality that their biosynthesis couldn’t be directly infered from the DNA design.

The development of a big number of rather new technologies for exploring the structures of these sugar chains has opened up a new universe of molecular biology which has been named glycobiology. That word was first used in 1988 by Rademacher, Parekh, and Dwek to talk about the union of the traditional disciplines of carbohydrate chemistry and biochemistry with modern comprehension of the cellular and molecular biology of glycans. The word glycobiology has gainedwide acceptance, with a larger biomedical journal, a growing scientific society, and a Gordon Research Conference now using this name.

Defined in the larger sense, glycobiology is then the study of the morphology, biosynthesis, and biology of saccharides (sugar chains or glycans) that are widely distributed in nature. It’s one of the more rapidly areas in the biomedical sciences, with importance to basic study, biomedicine, and biotechnology. Indeed, several biotechnology, pharmaceutical, and laboratory supply business have invested heavily in the matter.

The area goes from the chemistry of carbohydrates and the enzymology of glycan-modifying proteins to the functions of glycans in heterogeneous biological systems, and their use by a number of techniques.

Research in glycobiology requires a basis not only in the nomenclature, biosynthesis, morphology, chemical synthesis, and actions of heterogeneous glycans, but also in the general disciplines of molecular genetics, cellular biology, physiology, and protein chemistry. This volume gives a comprehensive view of the area of glycobiology, with a special emphasis on the glycans of higher animal systems, about which the biggest quantity is actually known. It’staked for granted that who is reading has a basic knowledge in graduate-level chemistry, biochemistry, and cell biology.

In recent years, research of a class of linear glycans recognized as glycosaminoglycans (or GAGs for short), and particularly a sub-set known as HSGAGs, which are build up of heparan sulfate and its relative heparin have shed a good deal of light on the role of the snail secretions we use to fabricate the snail treatment cream.

The complex snail secretions contribute to the correct assembling neccesary for healthy skin repair, skin regeneration and skin renewal.

BIO SKIN BALM - Rescues your skin from the ravages of eczema, dermatitis, psoriasis, very dry skin, skin rashes, rosacea symptoms and more...

Boosts the production of the water holding molecules present in the dermis and retains water, induces the proliferation of antimicrobial peptides thatk keep skin infection at bay, moderates inflammation, relieves dryness and redness, unclogs pores while replenishing the lipid barrier of the skin to block the penetration of allergens. Stimulates the regeneration of damaged cells, prevents and removes scars, actinic keratosis, psoriasis scales and removes all types of skin blemishes.

Made in the USA. One Month's supply 50 grams = 1.76 oz

Regular Price for 50 Gram Bottle: $69.99

Get rid of scars and blemishes, while restoring a healthy level of moisture and protecting and renewing that beautiful you

Boosts the production of antimicrobials, moderates inflammatory reactions, unclogs pores and deeply moisturizes skin while replenishing the lipid barrier of the skin and stimulating the regeneration of damaged cells, preventing and removing scars, actinic keratosis, psoriasis scales and all types of skin blemishes.

Made in the USA. One Month's supply 50 grams = 1.76 oz

Regular Price for 50 Gram Bottle: $69.98

Save at least 20% off price & save on domestic or world wide shipping costs
when you order more than one month's supply

Discount Price Two Bottles: $55.98 each, at checkout within our secure shopping cart.
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Natural Acne Gel, Rosacea Remedy & Scar Healing

This gel is an oil free product and is a biological remedy for acne, rosacea, and scar healing with moisturizing seaweed extracts. Best for people with very oily skin conditions. All our products are safe for children, moms-to-be and breast fedding mothers.

Made in the USA. One Month's supply 50 grams = 1.76 oz

50 Grams in One Airless Pump Bottle: $59

Save at least 20% off price & save on domestic or world wide shipping costs
when you order more than one month's supply

Discount Price Two Bottles: $39.20 each, at checkout within our secure shopping cart.

Ultra Exfoliate Your Skin with BIOSKINEXFOL

A home microdermabrasion cream with high quality micro-crystals, the same professionals use to breakdown hard, rough and old scar tissues, and allow for a deeper penetration of our exclusive all natural skin moisturizing and regeneration complex contained in the microdermabrasion cream. For ice-pick acne scars and for old and rough scars and actinic keratosis scales. Not for keloids.

Made in the USA. Two to Three Month's supply 120 grams = 4.23 oz

120 Gram Bottle: $89

Check also our specialty natural skin care products: BIOSKINEXFOL Home Microdermabrasion Cream for ultra exfoliation of rough and old scars and to reduce ice pick acne scars, BIO SKIN REJUVENATION CREAM to get rid of brown sun spots, and BIO STRETCH MARK CREAM for the prevention and treatment of new stretch marks.